To help you get the best out of your visit to the
Biochemical Journal, papers are divided into nine knowledge environments:
Cell,
ChemBio,
Disease,
Energy,
Gene,
Metabolism,
Plant,
Signal,
Structure
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US Symposium, March 22nd 2012 - Free Registration
In gratitude to the Sanford-Burnham Medical Research Institute for hosting its US Editorial Office, the
Biochemical Journal is sponsoring a special one-day symposium at the Institute in La Jolla, CA on Thursday March 22nd 2012.
View speaker list and pre-register.
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In this BJ Signal paper, which is freely available to all readers, Dario Alessi and colleagues show that interaction of WNK [with no lysine (K) kinase] isoforms is not essential for their T-loop phosphorylation and activation, and conclusively establish that full-length WNK1, WNK2 and WNK3, but not WNK4, are capable of directly phosphorylating Ser382 of WNK1 in vitro.
In this BJ Cell paper, which is freely available to all readers, Harald Stenmark and colleagues demonstrate that the ubiquitin ligase Nedd4 is a novel binding partner of Beclin 1, and that Nedd4 polyubiquitinates Beclin 1 with Lys11- and Lys63-linked chains.
In this BJ Energy paper, which is freely available to all readers, Michael Davies and colleagues show that selenocysteine residues are oxidized rapidly by HOSCN (hypothiocyanous acid), with the resultant inhibition of the critical intracellular selenocysteine-dependent protective enzymes glutathione peroxidase and thioredoxin reductase.
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